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The Mu Opioid Receptor Genotype May be a Marker for Those Who Drink for Alcohol's Rewarding Effects, University of California, Los Angeles (UCLA) Study


12/17/2012 7:32:36 AM

Previous research had identified an individual's subjective response to alcohol as a marker of alcoholism risk. The A118G single nucleotide polymorphism (SNP) of the mu opioid receptor (OPRM1) gene had also been previously associated with subjective response to alcohol in heavy drinkers. A new study extends this research, showing that the OPRM1 genotype seems to moderate the pleasant and stimulating effects to alcohol among alcohol-dependent (AD) individuals but not its unpleasant and sedative effects.

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